Detection and Identification of Poisons by High Performance Liquid Chromatography Mass Spectrometry HPLCMS in Clinical and Forensic Toxicology

Introduction

Take This Course

The scientific committee observed there are shortage knowledge and skills among our target groups about the HPLC in clinics and related tests, which as following:
- Lack of awareness for meaning of all the parameters in an HPLC analytical method and it’s application in clinical and forensic toxicology in health sector.
- Weakness about running the methods of HPLC and how to analyze biological samples containing toxicines in toxicated patients.
- Mixation among biological toxins produced by certain microorganisms, animals, and plants and other drugs.

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Note : the first 2 days from " 04 – 05 Des 2022 " will be online only via VMA
and the last 3 days will be onsite at The research Lab of the Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, SA.

Objectives

Describe the meaning of all param
eters in HPLC analytical method.
Identify how to follow an HPLC analytical method to set up an HPLC system for poisons analysis and their identification by HPLC/MS.
Practice how to run HPLC analytical methods and interpretation of chromatographic results.
Demonstrate how to run HPLC, develop HPLC methods, and sample preparation for analysis of poisons or toxins in biological fluids.
Developing HPLC methods for challenging separations of complicated mixtures of biological samples of trace poisons or unknown poisons and to troubleshoot HPLC.
Compare and analyze all drugs, drugs of abuse and biological toxins.
Differentiate biological toxins produced by certain microorganisms, animals, and plants. Examples of toxins of biological origin (Diphtheria Toxin, Tetrodotoxin, Pertussis Toxin, Botulinum Toxin, Snake Venom Toxins, Conotoxin, Ricin and Cyanobacteria).

VAT Included
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